RNA Details
Disease Name
atrial fibrillation
Tissue
heart
RNA Symbol
miR-223-3p
RNA ID
MIMAT0000280
RNA Type
miRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
NA
Target
FOXO3
Pathway
NA
PubMed ID
34097559
Title
Quercetin prevents isoprenaline-induced myocardial fibrosis by promoting autophagy via regulating miR-223-3p/FOXO3
Year
2021
Function
"Quercetin (Que) can effectively inhibit the expression of miR-223-3p in atrial fibrillation model cells and rats myocardial tissues, and meanwhile enhance the expression of FOXO4 and activate the autophagy pathway, and significantly inhibit myocardial fibrosis, and improve myocardial remodeling in atrial fibrillation."